Aurélie FILDIER

Engineer

Contact

aurelie.fildier[@]isa-lyon.fr

Biography

Aurélie Fildier was hired CNRS in 2000 as support staff in the Service Central d’Analyse (USR59- Lyon) in the Organic and Isotopy group. Studying chemistry in evening classes, she graduated from IUT of Chemistry (Université Lyon1) in 2002 and from CNAM (Lyon) in 2005 (DEST).
In 2007, she joined the mass spectrometry team of the SCA and worked on R&D project and analytical services. In 2013, she was an assistant engineer and worked in research team TRACES at ISA.
She is a specialist of non targeted analytical strategy based on liquid chromatography (LC-QToF and nanoLC-QToF) coupled with High Resolution Mass Spectrometry and MALDI-ToF technology, for the detection and the identification of unknown compounds (contaminants, endogenous or exogenous metabolites) in complex environmental and biological matrices.

Publications

Publications HAL de Aurelie,Fildier

2023

Journal articles

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Juliane Hollender, Emma L. Schymanski, Lutz Ahrens, Nikiforos Alygizakis, Frederic Béen, et al.. NORMAN guidance on suspect and non-target screening in environmental monitoring. Environmental Science Europe, 2023, 35 (1), 75 (61p.). ⟨10.1186/s12302-023-00779-4⟩. ⟨hal-04204173⟩
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https://hal.science/hal-04204173/file/s12302-023-00779-4.pdf BibTex

2022

Journal articles

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Emmanuelle Lebeau-Roche, Gaëlle Daniele, Aurélie Fildier, Christelle Bonnefoy, Cyril Turiès, et al.. Time and dose-dependent impairment of liver metabolism in Gasterosteus aculeatus following exposure to diclofenac (DCF) highlighted by LC-HRMS untargeted metabolomics. Science of the Total Environment, 2022, pp.159801. ⟨10.1016/j.scitotenv.2022.159801⟩. ⟨hal-03839504⟩
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https://hal.science/hal-03839504/file/Version%20auteur%20ELebeau.pdf BibTex

2021

Journal articles

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Emmanuelle Lebeau-Roche, Gaëlle Daniele, Aurélie Fildier, Cyril Turies, Odile Dedourge-Geffard, et al.. An optimized LC-HRMS untargeted metabolomics workflow for multi-matrices investigations in the three-spined stickleback. PLoS ONE, 2021, 16 (11), pp.e0260354. ⟨10.1371/journal.pone.0260354⟩. ⟨hal-03423291v2⟩
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https://hal.science/hal-03423291/file/2022-020.pdf BibTex
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Laure Wiest, Antoine Gosset, Aurélie Fildier, Christine Libert, Matthieu Hervé, et al.. Occurrence and removal of emerging pollutants in urban sewage treatment plants using LC-QToF-MS suspect screening and quantification. Science of the Total Environment, 2021, 774, pp.145779. ⟨10.1016/j.scitotenv.2021.145779⟩. ⟨hal-03162034⟩
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https://univ-lyon1.hal.science/hal-03162034/file/Wiest%282021%29-STOTEN-vauteur.pdf BibTex
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Coralie Soulier, Virginie Boiteux, Patrick Candido, Emilie Caupos, Mathilde Chachignon, et al.. La spectrométrie de masse haute résolution pour la recherche de micropolluants organiques dans l’environnement. Techniques Sciences Méthodes , 2021, 6, pp.43-54. ⟨10.36904/tsm/202106043⟩. ⟨hal-03274374⟩
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https://hal.science/hal-03274374/file/margoum-et-al_qualite-eaux_2020-02-REV.pdf BibTex
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Antoine Gosset, Laure Wiest, Aurélie Fildier, Christine Libert, Barbara Giroud, et al.. Ecotoxicological risk assessment of contaminants of emerging concern identified by “suspect screening” from urban wastewater treatment plant effluents at a territorial scale. Science of the Total Environment, 2021, 778, pp.146275. ⟨10.1016/j.scitotenv.2021.146275⟩. ⟨hal-03167988⟩
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https://univ-lyon1.hal.science/hal-03167988/file/2021-STOTEN146275.pdf BibTex
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Bastian Schulze, Denice van Herwerden, Ian Allan, Lubertus Bijlsma, Nestor Etxebarria, et al.. Inter-laboratory mass spectrometry dataset based on passive sampling of drinking water for non-target analysis. Scientific Data , 2021, 8 (1), pp.223. ⟨10.1038/s41597-021-01002-w⟩. ⟨hal-03325586⟩
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https://enpc.hal.science/hal-03325586/file/Schulze%20et%20al_2021_Inter-laboratory%20mass%20spectrometry%20dataset%20based%20on%20passive%20sampling%20of.pdf BibTex

2020

Journal articles

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Samia Selmi-Ruby, Jesús Marín-Sáez, Aurélie Fildier, Audrey Buleté, Myriam Abdallah, et al.. In vivo characterisation of the toxicological properties of DPhP, one of the main degradation products of aryl phosphate esters. Environmental Health Perspectives, 2020, 128 (12), ⟨10.1289/EHP6826⟩. ⟨hal-03013621⟩
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https://hal.science/hal-03013621/file/EHP6826.pdf BibTex

2019

Journal articles

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Lucie Pinasseau, Laure Wiest, Aurélie Fildier, Laurence Volatier, Gary Fones, et al.. Use of passive sampling and high resolution mass spectrometry using a suspect screening approach to characterise emerging pollutants in contaminated groundwater and runoff. Science of the Total Environment, 2019, 672, pp.253-263. ⟨10.1016/j.scitotenv.2019.03.489⟩. ⟨hal-02137023⟩
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https://univ-lyon1.hal.science/hal-02137023/file/S0048969719315050.pdf BibTex
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Christelle Bonnefoy, Aurélie Fildier, Audrey Buleté, Claire Bordes, Jeanne Garric, et al.. Untargeted analysis of nanoLC-HRMS data by ANOVA-PCA to highlight metabolites in Gammarus fossarum after in vivo exposure to pharmaceuticals. Talanta, 2019, 202, pp.221-229. ⟨10.1016/j.talanta.2019.04.028⟩. ⟨hal-02124467⟩
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https://hal.science/hal-02124467/file/S0039914019304175.pdf BibTex

2018

Journal articles

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Alexandre Bergé, Audrey Buleté, Aurélie Fildier, R. Mailler, Johnny Gasperi, et al.. Non-target strategies by HRMS to evaluate fluidized micro-grain activated carbon as a tertiary treatment of wastewater. Chemosphere, 2018, 213, pp.587-595. ⟨10.1016/j.chemosphere.2018.09.101⟩. ⟨hal-01879163⟩
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Alexandra Berlioz-Barbier, Audrey Buleté, Aurélie Fildier, Jeanne Garric, Emmanuelle Vulliet. Non-targeted investigation of benthic invertebrates ( Chironomus riparius ) exposed to wastewater treatment plant effluents using nanoliquid chromatography coupled to high-resolution mass spectrometry. Chemosphere, 2018, 196, pp.347-353. ⟨10.1016/j.chemosphere.2018.01.001⟩. ⟨hal-01744706⟩
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2017

Journal articles

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Alexandre Bergé, Audrey Buleté, Aurélie Fildier, Emmanuelle Vulliet. High-Resolution Mass Spectrometry as a Tool To Evaluate the Sample Preparation of Sludge. Analytical Chemistry, 2017, 89 (18), pp.9685-9694. ⟨10.1021/acs.analchem.7b01081⟩. ⟨hal-01583333⟩
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2016

Journal articles

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Nizar Ben Salah, Hervé Casabianca, Ismahen Essaidi, Sophie Chenavas, Aurélie Fildier, et al.. Isolation and structure elucidation of two new antioxidant flavonoid glycosides and fatty acid composition in Hedysarum carnosum Desf.. Industrial Crops and Products, 2016, 81, pp.195-201. ⟨10.1016/j.indcrop.2015.11.057⟩. ⟨hal-01355597⟩
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2015

Journal articles

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Nizar Ben Salah, Hervé Casabianca, Hichem Ben Jannet, Sophie Chenavas, Sanglar Corinne, et al.. Phytochemical and biological investigation of two diplotaxis species growing in Tunisia: D-virgata & D-erucoides. Molecules, 2015, 20 (10), pp.18128-18143. ⟨10.3390/molecules201018128⟩. ⟨hal-01356843⟩
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Haythem Bennour, Aurélie Fildier, Saber Chatti, Hans R. Kricheldorf, Mongia Said Zina, et al.. Biosourced Cyclic and Multicyclic Polyesters Based on 1,4:3,6-Dianhydrohexitols: Application to Metal Ions Uptake in Aqueous Media. Macromolecular Chemistry and Physics, 2015, 216 (10), pp.1081-1090. ⟨10.1002/macp.201500001⟩. ⟨hal-01165292⟩
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Chaouki Belgacem, Raouf Medimagh, Aurélie Fildier, Audrey Buleté, Hans R. Kricheldorf, et al.. Synthesis and characterization of isosorbide-based alpha,omega-dihydroxyethersulfone oligomers. Designed Monomers and Polymers, 2015, 18 (1), pp.64-72. ⟨10.1080/15685551.2014.947554⟩. ⟨hal-01187447⟩
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Chaouki Belgacem, Raouf Medimagh, Aurélie Fildier, Audrey Buleté, Hans R. Kricheldorf, et al.. Synthesis and characterization of isosorbide-based α,ω-dihydroxyethersulfone oligomers. Designed Monomers and Polymers, 2015, 18 (1), pp.64-72. ⟨10.1080/15685551.2014.947554⟩. ⟨hal-01070696⟩
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2014

Journal articles

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Raouf Medimagh, Asma Saadaoui, Salma Mghirbi, Sylvain Marque, Damien Prim, et al.. New biosourced alternated poly(ether)Ester-Amides (PeEA): synthesis and combined NMR/MALDI ToF MS characterization. Journal of Polymer Research, 2014, 21 (6), pp.article 486. ⟨10.1007/s10965-014-0486-4⟩. ⟨hal-01057926⟩
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Haythem Bennour, Raouf Medimagh, Aurélie Fildier, Guy Raffin, Marie Hangouët, et al.. Hyperbranched cyclic and multicyclic poly(etherketone)s by polycondensation of isosorbide and isomannide with 2,6,4′-trifluorobenzophenone and 1,3,5-tris(4-fluorobenzoyl) benzene. High Performance Polymers, 2014, 26 (2), pp.144-155. ⟨10.1177/0954008313501912⟩. ⟨hal-00965439⟩
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2013

Journal articles

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Raouf Medimagh, Salma Mghirbi, Asma Saadaoui, Aurélie Fildier, Marlène Desloir-Bonjour, et al.. Synthesis of biosourced polyether-amides from 1,4-3,6-dianhydrohexitols: Characterization by NMR and MALDI-ToF mass spectrometry. Comptes Rendus. Chimie, 2013, 16 (12), pp.1127-1139. ⟨10.1016/j.crci.2013.05.004⟩. ⟨hal-00905733⟩
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Agnèta Kiss, Marianna Lucio, Aurélie Fildier, Corinne Buisson, Philippe Schmitt-Kopplin, et al.. Doping control using high and ultra-high resolution mass spectrometry based non-targeted metabolomics-A case study of salbutamol and budesonide abuse. PLoS ONE, 2013, 8 (9), pp.e74584. ⟨10.1371/journal.pone.0074584⟩. ⟨hal-00865161⟩
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Sonia Fekih-Zaghbib, Aurélie Fildier, Sami Barrek, Balkiss Bouhaouala-Zahar. A complementary LC-ESI-MS and MALDI-TOF approach for screening antibacterial proteomic signature of farmed European Sea bass mucus. Fish and Shellfish Immunology, 2013, 35 (2), pp.207-212. ⟨10.1016/j.fsi.2013.04.017⟩. ⟨hal-00915187⟩
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Hana Ben Abderrazak, Aurélie Fildier, Hatem Ben Romdhane, Saber Chatti, Hans R. Kricheldorf. Synthesis of new poly(ether ketone)s derived from biobased diols. Macromolecular Chemistry and Physics, 2013, 214 (13), pp.1423-1433. ⟨10.1002/macp.201300015⟩. ⟨hal-00850452⟩
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Saber Chatti, Steffen M. Weidner, Aurélie Fildier, Hans R. Kricheldorf. Copolyesters of isosorbide, succinic acid, and isophthalic acid: Biodegradable, high T-g engineering plastics. Journal of polymer science. Part A-1, Polymer chemistry, 2013, 51 (11), pp.2464-2471. ⟨10.1002/pola.26635⟩. ⟨hal-00993086⟩
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2011

Journal articles

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Hana Ben Abderrazak, Aurélie Fildier, Sylvain Marque, Damien Prim, Hatem Ben Rhomdhane, et al.. Cyclic and non cyclic aliphatic-aromatic polyesters derived from biomass: Study of structures by MALDI-ToF and NMR. European Polymer Journal, 2011, 47 (11), pp.2097-2110. ⟨10.1016/j.eurpolymj.2011.07.009⟩. ⟨hal-00639329⟩
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