Karine FAURE

Chromatography & Hyphenated Techniques, Team leader
CNRS researcher, PhD

Contact

karine.faure[@]isa-lyon.fr

Research

  • Development of multidimensional separation techniques for preparative purposes involving centrifugal partition chromatography, liquid chromatography and supercritical fluid chromatography
  • Development of comprehensive LC x SFC separation for the analysis of neutral compounds
  • Development of LC x LC x IM-HRMS for the characterization of complex samples
  • Application to natural products and biomass derivatives

Biography

Karine Faure is a research scientist at the French National Centre for Scientific Research (CNRS) since 2007. She graduated from Toulouse National Chemistry School (ENSCT) and received an MSc degree in analytical chemistry from University College Cork (Ireland). Her PhD was completed in the group of Prof JD Glennon in 2006. She received her Habilitation (HDR) in 2013 and since supervised 7 PhD students and over 15 MSc students. Interested in the development of multidimensional separation techniques for both analytical and preparative purposes, she has been involved in many industrial collaborative projects. She teaches liquid chromatography at CPELyon school of engineering. She is member of the editorial board of Journal of Chromatography and Related Technologies and Journal of Pharmaceutical Analysis. She is a permanent member of the International Committee of CCC conferences and president of Club Lyonnais de Chromatography, a national network of over 110 members.

She is the author of over 35 publications in international journals and 7 invited book chapters. Her work was presented as oral and poster communications in over 70 national and international conferences amongst which 8 invited talks.

Keywords

separation; chromatography; purification and separation processes

Publications

Articles in peer-review journals since 2011

Publications HAL de Karine,Faure

2023

Journal articles

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Eloïse Teboul, Eliise Tammekivi, Magali Batteau, Christophe Geantet, Karine Faure. Off-line two-dimensional separation involving supercritical fluid chromatography for the characterization of the wastewater from algae hydrothermal liquefaction. Journal of Chromatography A, 2023, 1694, pp.463907. ⟨10.1016/j.chroma.2023.463907⟩. ⟨hal-04037993⟩
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https://hal.science/hal-04037993/file/RafBioAlg%20_%20depot%20HAL.pdf BibTex

2022

Journal articles

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Fleur Marie Saint Germain, Karine Faure, Estelle Saunier, Jean-Michel Lerestif, Sabine Heinisch. On-line 2D-RPLC x RPLC – HRMS to assess wastewater treatment in a pharmaceutical plant. Journal of Pharmaceutical and Biomedical Analysis, 2022, 208, pp.114465. ⟨10.1016/j.jpba.2021.114465⟩. ⟨hal-03823578⟩
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https://hal.science/hal-03823578/file/2021%20Marie%20St%20Germain%20JPBA%20_%20proof%20authors.pdf BibTex
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Magali Batteau, Karine Faure. Effect of the injection of water-containing diluents on band broadening in analytical supercritical fluid chromatography. Journal of Chromatography A, 2022, 1673, pp.463056. ⟨10.1016/j.chroma.2022.463056⟩. ⟨hal-03711565⟩
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https://hal.science/hal-03711565/file/220324_revised%20manuscript_author%20preprint.pdf BibTex

2021

Journal articles

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Marion Burlet-Parendel, Karine Faure. Opportunities and challenges of liquid chromatography coupled to supercritical fluid chromatography. Trends in Analytical Chemistry, 2021, 144, pp.116422. ⟨10.1016/j.trac.2021.116422⟩. ⟨hal-03326884⟩
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https://hal.science/hal-03326884/file/2021_Faure-TRAC_Opportunities-challenges-liquid-chromatography-coupled-supercritical-fluid-chromatography.pdf BibTex
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Lucile Lecas, Sylvie Nuccio, René Vaumas, Karine Faure. Off‐line two‐dimensional liquid chromatography separation for the quality control of saponins samples from Quillaja Saponaria. Journal of Separation Science, 2021, 44 (16), pp.3070- 3079. ⟨10.1002/jssc.202100115⟩. ⟨hal-03317997⟩
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https://hal.science/hal-03317997/file/2021_JSepSci_Off-line%20two-dimensional-liquid-chromatography-separation-quality-control-saponins-samples-Quillaja-Saponaria.pdf BibTex

2020

Journal articles

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Léa Marlot, Magali Batteau, Karine Faure. Classification of biphasic solvent systems according to Abraham descriptors for countercurrent chromatography. Journal of Chromatography A, 2020, 1617, pp.460820. ⟨10.1016/j.chroma.2019.460820⟩. ⟨hal-02436965⟩
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https://hal.science/hal-02436965/file/2020-JCA-Marlot-Batteau-Faure-Classification%20of%20biphasic%20solvent%20systems%20according%20to%20Abraham%20descriptors%20for%20countercurrent%20chromatography.pdf BibTex
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Luca Pompermaier, Stefan Schwaiger, Monizi Mawunu, Thea Lautenschlaeger, Hermann Stuppner, et al.. Purification of thonningianins A and B and four further derivatives from Thonningia sanguinea by one‐ and two‐dimensional centrifugal partition chromatography. Journal of Separation Science, 2020, 43 (2), pp.524-530. ⟨10.1002/jssc.201900811⟩. ⟨hal-02338304⟩
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https://hal.science/hal-02338304/file/2020-JournalSeparationScience_Pompermaier-Purification-Thonningianins.pdf BibTex

2018

Journal articles

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Léa Marlot, Magali Batteau, Dalene de Beer, Karine Faure. In silico screening of comprehensive two-dimensional centrifugal partition chromatography x liquid chromatography for multiple compounds isolation. Analytical Chemistry, 2018, 90 (24), pp.14279-14286. ⟨10.1021/acs.analchem.8b03440⟩. ⟨hal-01937324⟩
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https://hal.science/hal-01937324/file/2018-AnalChem-Marlot-Batteau-deBeer-Faure-In%20silico%20screening%20of%20comprehensive%20two-dimensional%20centrifugal%20partition%20chromatography%20x%20liquid%20chromatography%20for%20multiple%20compounds%20isolation.pdf BibTex
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Léa Marlot, Magali Batteau, Karine Faure. Comparison between centrifugal partition chromatography and preparative liquid chromatography as first dimensions in off-line two-dimensional separation: Application to the isolation of multi-targeted compounds from Edelweiss plant. Electrophoresis, 2018, 39 (15), pp.2011-2019. ⟨10.1002/elps.201800032⟩. ⟨hal-01809502⟩
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https://hal.science/hal-01809502/file/2018%20Electrophoresis%20Marlot-BAtteau-Faure-Comparison%20between%20centrifugal%20partition%20chromatography.pdf BibTex
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José Cheel, Jan Hájek, Marek Kuzma, Kumar Saurav, Iva Smykalova, et al.. Application of HPCCC Combined with Polymeric Resins and HPLC for the Separation of Cyclic Lipopeptides Muscotoxins A–C and Their Antimicrobial Activity. Molecules, 2018, 23 (10), pp.2653. ⟨10.3390/molecules23102653⟩. ⟨hal-01963293⟩
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https://hal.science/hal-01963293/file/2018%20Molecules-Cheel-Application%20of%20HPCCC%20combined%20with%20polymeric%20resins%20and%20HPLC%20.pdf BibTex

2017

Journal articles

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Léa Marlot, Magali Batteau, Marie-Claire Escofet, Sylvie Nuccio, Véronique Coquoin, et al.. Two-dimensional multi-heart cutting centrifugal partition chromatography–liquid chromatography for the preparative isolation of antioxidants from Edelweiss plant. Journal of Chromatography A, 2017, 1504, pp.55-63. ⟨10.1016/j.chroma.2017.04.056⟩. ⟨hal-01569418⟩
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https://hal.science/hal-01569418/file/2017%20JCA-Marlot-Two-dimensional%20multi-heart%20cutting%20CPC-LC.pdf BibTex
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Fériel Bouiche, Karine Faure. In-situ protein determination to monitor contamination in a centrifugal partition chromatograph. Analytical Biochemistry, 2017, 525, pp.23-28. ⟨10.1016/j.ab.2017.02.015⟩. ⟨hal-01518929⟩
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https://hal.science/hal-01518929/file/2017%20analBiochem-Bouiche-Faure-In-situ%20protein%20determination%20to%20monitor%20contamination%20in%20a%20centrifugal%20partition%20chromatograph.pdf BibTex
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Léa Marlot, Karine Faure. Preparative two dimensional separations involving liquid–liquid chromatography. Journal of Chromatography A, 2017, 1494, pp.1-17. ⟨10.1016/j.chroma.2017.03.031⟩. ⟨hal-01515553⟩
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https://hal.science/hal-01515553/file/2017%20JCA%20Marlot-Faure%20-%20Preparative%20two%20dimensional%20separations%20involving%20Liquid-Liquid%20Chromatography.pdf BibTex
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Josiane Saadé, Nina Declas, Pedro Marote, Claire Bordes, Karine Faure. Functionalization of cyclic olefin copolymer substrates with polyethylene glycol diacrylate for the in situ synthesis of immobilized nanoparticles. Journal of Materials Science, 2017, 52 (8), pp.4509-4520. ⟨10.1007/s10853-016-0696-8⟩. ⟨hal-01515322⟩
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https://hal.science/hal-01515322/file/2017%20J%20Materials%20Sciences-Saade-Declas-Marote-Bordes-Faure-%20Functionalization%20of%20cyclic%20olefin%20copolymer%20substrates%20.pdf BibTex
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José Cheel, Petra Urajová, Jan Hájek, Pavel Hrouzek, Marek Kuzma, et al.. Separation of cyclic lipopeptides puwainaphycins from cyanobacteria by HPCCC combined with polymeric resins and HPLC. Analytical and Bioanalytical Chemistry, 2017, 409 (4), pp.917-930. ⟨10.1007/s00216-016-0066-z⟩. ⟨hal-01515308⟩
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https://hal.science/hal-01515308/file/2017%20AnalBioanlChem-Cheel-Separation%20of%20cyclic%20lipopeptides%20puwainaphycins.pdf BibTex

2016

Journal articles

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Norbert Fumat, Alain Berthod, Karine Faure. Effect of operating parameters on a centrifugal partition chromatography separation. Journal of Chromatography A, 2016, 1474, pp.47-58. ⟨10.1016/j.chroma.2016.10.014⟩. ⟨hal-01515264⟩
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https://hal.science/hal-01515264/file/2016%20JCA-Fumat-Berthod-Faure-Effect%20of%20operating%20parameters%20on%20a%20Centrifugal%20Partition%20Chromatography%20separation.pdf BibTex
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Elodie Bouju, Alain Berthod, Karine Faure. Carnosol purification. Scaling-up centrifugal partition chromatography separations. Journal of Chromatography A, 2016, 1466, pp.59-66. ⟨10.1016/j.chroma.2016.08.015⟩. ⟨hal-01515260⟩
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https://hal.science/hal-01515260/file/2016-JCA-Bouju-Berthod-Faure-Carnosol%20CPC.pdf BibTex
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Josiane Saadé, Claire Bordes, Guy Raffin, Marie Hangouët, Pédro Marote, et al.. Response surface optimization of miniemulsion: application to UV synthesis of hexyl acrylate nanoparticles. Colloid and Polymer Science, 2016, 294 (1), pp.27-36. ⟨10.1007/s00396-015-3778-2⟩. ⟨hal-01252718⟩
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2015

Journal articles

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Elodie Bouju, Alain Berthod, Karine Faure. Scale-up in centrifugal partition chromatography: The “free-space between peaks” method. Journal of Chromatography A, 2015, 1409, pp.70-78. ⟨10.1016/j.chroma.2015.07.020⟩. ⟨hal-01186354⟩
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https://hal.science/hal-01186354/file/2015-Bouju-Berthod-Faure-JCA-Scale-up.pdf BibTex
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Alain Berthod, Karine Faure. Revisiting resolution in hydrodynamic countercurrent chromatography: Tubing bore effect. Journal of Chromatography A, 2015, 1390, pp.71-77. ⟨10.1016/j.chroma.2015.02.053⟩. ⟨hal-01164863⟩
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2014

Journal articles

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Karine Faure, Elodie Bouju, Pauline Suchet, Alain Berthod. Limonene in Arizona liquid systems used in countercurrent chromatography. I Physicochemical properties.. Analytical and Bioanalytical Chemistry, 2014, 406 (24), pp.5909-5917. ⟨10.1007/s00216-014-8005-3⟩. ⟨hal-01073271⟩
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Karine Faure, Elodie Bouju, J. Doby, Alain Berthod. Limonene in Arizona liquid systems used in countercurrent chromatography. II Polarity and stationary-phase retention. Analytical and Bioanalytical Chemistry, 2014, 406 (24), pp.5919-5926. ⟨10.1007/s00216-014-8030-2⟩. ⟨hal-01073273⟩
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2013

Journal articles

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Karine Faure, Elodie Bouju, Pauline Suchet, Alain Berthod. Use of limonene in countercurrent chromatography: a green alkane substitute.. Analytical Chemistry, 2013, 85 (9), pp.4644-4650. ⟨10.1021/ac4002854⟩. ⟨hal-00876113⟩
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Karine Faure, Nazim Mekaoui, Jérémy Meucci, Alain Berthod. Solvent selection in countercurrent chromatography using small-volume hydrostatic columns. LCGC North America, 2013, 31 (2), pp.132-143. ⟨hal-00859788⟩
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A. Assoumani, M. Margoum, Y. Lassalle, Bernard Herbreteau, Karine Faure, et al.. Polydimethylsiloxane Rods for the Passive Sampling of Pesticides in Surface Waters. Water, 2013, 5, p. 1366 - p. 1379. ⟨10.3390/w5031366⟩. ⟨hal-00873142⟩
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https://hal.science/hal-00873142/file/ly2013-pub00038956.pdf BibTex

2012

Journal articles

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Yoann Ladner, Gérard Crétier, Karine Faure. Electrochromatography on acrylate-based monolith in cyclic olefin copolymer microchip: A cost-effective and easy-to-use technology. Electrophoresis, 2012, 33 (19-20), pp.3087-3094. ⟨10.1002/elps.201200238⟩. ⟨hal-00799854⟩
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https://hal.science/hal-00799854/file/2012%20Electrophoresis%20-%20Ladner-cretier-Faure%20Electrochromatography%20on%20acrylate-based%20monolith%20in%20cyclic%20olefin%20copolymer%20microchip.pdf BibTex
ref_biblio
Yoann Ladner, Gérard Crétier, Karine Faure. Electrochromatography on acrylate-based monolith in cyclic olefin copolymer microchip: A cost-effective and easy-to-use technology. Electrophoresis, 2012, 33 (19-20), pp.3087-3094. ⟨10.1002/elps.201200238⟩. ⟨hal-04152205⟩
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Yoann Ladner, Gérard Crétier, Karine Faure. Fabrication of acrylate monolith using photopolymerization: Effect of light intensity on electrochromatographic performance. Journal of Separation Science, 2012, 35 (15), pp.1940-1944. ⟨10.1002/jssc.201200165⟩. ⟨hal-00799846⟩
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https://hal.science/hal-00799846/file/2012%20JSS-ladner-cretier-Faure%20Fabrication%20of%20acrylate%20monolith%20using%20photopolymerization.pdf BibTex
ref_biblio
Yoann Ladner, Gérard Crétier, Karine Faure. Fabrication of acrylate monolith using photopolymerization: Effect of light intensity on electrochromatographic performance. Journal of Separation Science, 2012, 35 (15), pp.1940-1944. ⟨10.1002/jssc.201200165⟩. ⟨hal-04152202⟩
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Nazim Mekaoui, Karine Faure, Alain Berthod. Advances in countercurrent chromatography for protein separations. Bioanalysis, 2012, 4 (7), pp.833-844. ⟨10.4155/BIO.12.27⟩. ⟨hal-00799824⟩
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Clément Faye, Joseph Chamieh, Thomas Moreau, Fabien Garnier, Karine Faure, et al.. In situ characterization of antibody grafting on porous monolithic supports. Analytical Biochemistry, 2012, 420 (2), pp.147-154. ⟨10.1016/j.ab.2011.09.016⟩. ⟨hal-00698239⟩
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Yoann Ladner, Anthony Bruchet, Gérard Crétier, Vincent Dugas, Jérôme Randon, et al.. New “one-step” method for the simultaneous synthesis and anchoring of organic monolith inside COC microchip channels. Lab on a Chip, 2012, 12 (9), pp.1680. ⟨10.1039/c2lc21211k⟩. ⟨hal-04152210⟩
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Yoann Ladner, Anthony Bruchet, Gérard Crétier, Vincent Dugas, Jérôme Randon, et al.. New "one-step" method for the simultaneous synthesis and anchoring of organic monolith inside COC microchip channels. Lab on a Chip, 2012, 12 (9), pp.1680-1685. ⟨10.1039/c2lc21211k⟩. ⟨hal-00799836⟩
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https://hal.science/hal-00799836/file/2012-Lab%20on%20a%20Chip-%20Ladner-COC-microchip-channel%20.pdf BibTex

 

Direction of books or issues of journals – books – book chapters

Publications HAL de karine,faure

2016

Book sections

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Karine Faure. Chromatographie de partage centrifuge. Principes et applications.. Chromatographie et techniques séparatives, Editions T.I., pp.P1496, 2016. ⟨hal-01515525⟩
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2015

Book sections

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Alain Berthod, Karine Faure. Separations with a Liquid Stationary Phase: Countercurrent Chromatography or Centrifugal Partition Chromatography. Anderson J. L., Berthod A., Pino Estévez V., Stalcup A. M. Analytical Separation Science, 4, Wiley-VCH Verlag GmbH & Co. KGaA., pp.1177-1206, 2015, 9783527678129. ⟨10.1002/9783527678129.assep046⟩. ⟨hal-01255453⟩
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Alain Berthod, Karine Faure. Solvents in chromatography and electrophoresis. Anderson J. L., Berthod A., Pino Estévez V., Stalcup A. M. Analytical Separation Science, 1, Wiley-VCH Verlag GmbH & Co. KGaA., pp.135-158, 2015, 9783527678129. ⟨10.1002/9783527678129.assep007⟩. ⟨hal-01356733⟩
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Yoann Ladner, Gérard Crétier, Karine Faure. Electrochromatography on acrylate-based monolith in cyclic olefin copolymer microchip: an attractive technology. Van Schepdael A. (Ed). Microchip capillary electrophoresis protocols., 1274, Springer Science+Business Media, pp.161-167, 2015, Methods in molecular biology, 978-1-4939-2352-6. ⟨10.1007/978-1-4939-2353-3_14⟩. ⟨hal-01187522⟩
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2014

Book sections

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Karine Faure, Nazim Mekaoui, Alain Berthod. Saving solvents in chromatographic purifications: the counter-current chromatography technique. Inamuddin, D., Mohammad, A. (Eds.). Green chromatographic techniques. Separation and purification of organic and inorganic analytes, Springer, pp.1-18, 2014, 978-94-007-7734-7. ⟨hal-00983090⟩
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