Francesca BELLAGAMBI
Contact
ResearchGate/ Francesca_Bellagambi2
LinkedIn/in/ francesca-bellagambi-35852933Research
Ongoing Research focuses on biomarkers determination and analytical validation of biosensors for the diagnosis and monitoring in human health. Francesca BELLAGAMBI contributes to two research projects:
- development and validation of biosensors for the determination of peptide epitopes linked to hazelnut and peanut allergy – Project POC4Allergies – Point-of-Care system for personalized diagnosis and assessment of treatment efficacy for allergies (Project ID: ERAPERMED2019-127) coordinated by Abdelhamid Errachid (ISA)
- antibodies functionalization of nanoparticles to detect specific heart failure antigens in saliva as well as development and validation of biosensors for the determination of salivary biomarkers of heart failure – Project KardiaTool – An integrated POC solution for non-invasive diagnosis and therapy monitoring of Heart Failure patients (EU H2020 Project ID: 768686) coordinated by A. Errachid (ISA) – http://www.kardiatool.eu/
Biography
Dr. Francesca G. Bellagambi graduated in Analytical Toxicology in 2007 from the Faculty of Pharmacy, and in Chemistry cum laude in 2012 from the Department of Chemistry and Industrial Chemistry (DCCI), both from the University of Pisa, Italy. In 2016, she hold a doctorate degree cum laude in Chemistry and Materials Science from the DCCI. From 2016 to 2019 she was post-doctoral researcher at University of Pisa and her research activities were mainly focused on analytical methods (e.g. chromatography, mass spectrometry, hyphenated techniques, and immunochemical methods) for the determination of chemical biomarkers in biological fluids (e.g. oral fluid and exhaled breath) for the diagnosis and monitoring of diseases. In April 2019, she joined the Institute for Analytical Science in April 2019 as a post-doctoral researcher, working on analytical methods and biosensor development and validation for disease detection by saliva analysis.
Francesca BELLAGAMBI received twice the Seal of Excellence Certificate for two proposals within Marie Skodowska-Curie actions individual fellowships (2018, 2019). She is author of 29 articles in peer-reviewed journals (5 submitted)
Keywords
Publications
ORCID iD: 0000-0002-1608-8858 – Scopus Author iD: 55942967100
Publications (ISA affiliation)
2023
Journal articles
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- Hamdi Ben Halima, Francesca Bellagambi, Marie Hangouët, Albert Alcacer, Norman Pfeiffer, et al.. A novel electrochemical strategy for NT-proBNP detection using IMFET for monitoring heart failure by saliva analysis. Talanta, 2023, 251, pp.123759. ⟨10.1016/j.talanta.2022.123759⟩. ⟨hal-03996458⟩
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2022
Journal articles
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- Ibrahim Musa, Guy Raffin, Marie Hangouet, Marie Martin, Joan Bausells, et al.. Electrospun PVC-nickel phthalocyanine composite nanofiber based conductometric methanol microsensor. Microchemical Journal, 2022, 182, pp.107899. ⟨10.1016/j.microc.2022.107899⟩. ⟨hal-03997245⟩
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- Sawsen Azzouzi, Mounir Ben Ali, Francesca Bellagambi, Abdelhamid Elaïssari, Nicole Jaffrezic-Renault, et al.. Spatially hierarchical nano-architecture for real time detection of Interleukin-8 cancer biomarker. Talanta, 2022, 246, pp.123436. ⟨10.1016/j.talanta.2022.123436⟩. ⟨hal-03675524⟩
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- Ibrahim Musa, Guy Raffin, Marie Hangouet, Marie Martin, Albert Alcacer, et al.. Development of a Chitosan/Nickel Phthalocyanine Composite based Conductometric Micro‐sensor for Methanol Detection. Electroanalysis, 2022, pp.early access. ⟨10.1002/elan.202100707⟩. ⟨hal-03714065⟩
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2021
Journal articles
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- Hamdi Ben Halima, Francesca Bellagambi, Albert Alcacer, Pfeiffer Norman, Albert Heuberger, et al.. A silicon nitride ISFET based immunosensor for tumor necrosis factor-alpha detection in saliva. A promising tool for heart failure monitoring. Analytica Chimica Acta, 2021, 1161, pp.338468. ⟨10.1016/j.aca.2021.338468⟩. ⟨hal-03200127⟩
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- Aidonis Rammos, Aris Bechlioulis, Petros Kalogeras, Evanthia E Tripoliti, Yorgos Goletsis, et al.. Salivary biomarkers for diagnosis and therapy monitoring in patients with heart failure. A systematic review. Diagnostics, 2021, 11 (5), pp.824. ⟨10.3390/diagnostics11050824⟩. ⟨hal-03249942⟩
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- Francesca Bellagambi, Tommaso Lomonaco, Silvia Ghimenti, Denise Biagini, Roger Fuoco, et al.. Determination of peppermint compounds in breath by needle trap micro-extraction coupled with gas chromatography–tandem mass spectrometry. Journal of Breath Research, 2021, 15 (1), pp.016014. ⟨10.1088/1752-7163/abcdec⟩. ⟨hal-03113744⟩
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2020
Journal articles
- ref_biblio
- Silvia Ghimenti, Tommaso Lomonaco, Francesca Bellagambi, Denise Biagini, Pietro Salvo, et al.. Salivary lactate and 8-isoprostaglandin F2α as potential non-invasive biomarkers for monitoring heart failure: a pilot study. Scientific Reports, 2020, 10 (1), pp.Article Number: 7441. ⟨10.1038/s41598-020-64112-2⟩. ⟨hal-02926827⟩
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- Miguel Zea, Francesca Bellagambi, Hamdi Ben Halima, Nadia Zine, Nicole Jaffrezic-Renault, et al.. Electrochemical sensors for cortisol detections: Almost there. Trends in Analytical Chemistry, 2020, 132, pp.116058. ⟨10.1016/j.trac.2020.116058⟩. ⟨hal-03028233⟩
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- Pietro Salvo, Federico Vivaldi, Andrea Bonini, Denise Biagini, Francesca Bellagambi, et al.. Biosensors for Detecting Lymphocytes and Immunoglobulins. Biosensors, 2020, 10 (11), pp.155. ⟨10.3390/bios10110155⟩. ⟨hal-03113758⟩
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- Francesca Bellagambi, Tommaso Lomonaco, Pietro Salvo, Federico Vivaldi, Marie Hangouët, et al.. Saliva sampling: Methods and devices. An overview. Trends in Analytical Chemistry, 2020, 124, pp.115781. ⟨10.1016/j.trac.2019.115781⟩. ⟨hal-02534901⟩
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Publications (other affiliations)
Wilkinson M, White IR, Hamshere K, Holz O, Schuchardt S, Bellagambi FG, Lomonaco T, Biagini D, Di Francesco F, Fowler SJ. The peppermint breath test: a benchmarking protocol for breath sampling and analysis using GC-MS Journal of Breath Research 2021; 15 (2), 026006 10.1088/1752-7163/abd28c
Biagini D, Antoni S, Lomonaco T, Ghimenti S, Salvo P, Bellagambi FG, Scaramuzzo R, Ciantelli M, Cuttano A, Fuoco R, Di Francesco F. Micro-extraction by packed sorbent combined with UHPLC-ESI-MS/MS for the determination of prostanoids and isoprostanoids in dried blood spots Talanta 2020; 206, 120236 10.1016/j.talanta.2019.120236
Biagini D, Lomonaco T, Ghimenti S, Onor M, Bellagambi FG, Salvo P, Di Francesco F, Fuoco R. Using labelled internal standards to improve needle trap micro-extraction technique prior to gas chromatography/mass spectrometry Talanta 2019; 200, 145-155. 10.1016/j.talanta.2019.03.046
Barhoumi L, Bellagambi FG, Vivaldi FM, Baraket A, Clément Y, Zine N, Ben Ali M, Elaissari A, Errachid A. Ultrasensitive immunosensor array for TNF-α detection in artificial saliva using polymer-coated magnetic microparticles onto screen-printed gold electrode Sensors (Basel.) 2019; 19, 692. 10.3390/s19030692
Lomonaco T, Romani A, Ghimenti S, Biagini D, Bellagambi FG, Onor M, Salvo P, Fuoco R, Di Francesco F. Determination of carbonyl compounds in exhaled breath by on-sorbent derivatization coupled with thermal desorption and gas chromatography-tandem mass spectrometry Journal of Breath Research 2018; 12, 046004. 10.1088/1752-7163/aad202
Barhoumi L, Baraket A, Bellagambi FG, Karanasiou GS, Ben Ali M, Fotiadis DI, Bausells J, Zine N, Sigaud M, Errachid A. A novel chronoamperometric immunosensor for recombinant human TNF-α detection Sensors and Actuators B: Chemical 2018; 266, 477‒484. 10.1016/j.snb.2018.03.135
Paoletti C, He M, Salvo P, Melai B, Calisi N, Mannini M, Cortigiani B, Bellagambi FG, Swager TM, Di Francesco F, Pucci A. Room temperature amine sensors enabled by sidewall functionalization of single-walled carbon nanotubes RSC Advanced 2018; 8, 5578‒5585. 10.1039/C7RA13304A
Bellagambi FG, Degano I, Ghimenti S, T. Lomonaco T, V. Dini V, Romanelli M, Mastorci F, Gemignani A, Fuoco R, Di Francesco F. Determination of salivary a-amylase and cortisol in psoriatic subjects undergoing the Trier Social Stress Test Microchemical Journal 2018; 136, 177‒184. 10.1016/j.microc.2017.04.033
Lomonaco T, Ghimenti S, Biagini D, Bramanti E, Onor M, Bellagambi FG, Fuoco R, Di Francesco F. The effect of sampling procedures on the urate and lactate concentration in oral fluid Microchemical Journal 2018; 136, 255‒262. 10.1016/j.microc.2017.02.032
Ghimenti S, Lomonaco T, Biagini D, Bellagambi FG, Onor M, Trivella MG, Ruocco L, Pellegrini G, Di Francesco F, Fuoco R. Determination of warfarin and warfarin alcohols in dried blood spots by ultra-high performance liquid chromatography coupled to electrospray ionization-tandem mass spectrometry (UHPLC-ESI-MS/MS), Microchemical Journal 2018; 136, 247‒ 254. 10.1016/j.microc.2017.03.057
Salvo P, Melai B, Calisi N, Paoletti C, Bellagambi FG, Kirchhain A, Trivella MG, Fuoco R, Di Francesco F. Graphene-based devices for measuring pH Sensors and Actuators B: Chemical 2017; 256, 976‒991. 10.1016/j.snb.2017.10.037
Bellagambi FG, Baraket A, Longo A, Vatteroni M, Zine N, Bausells J, Fuoco R, Di Francesco F, Salvo P, Karanasiou GS, Fotiadis DI, Menciassi A, Errachid A. Electrochemical biosensor platform for TNF-a cytokines detection in both artificial and real human saliva: Heart Failure Sensors and Actuators B: Chemical 2017; 251, 1026‒1033. 10.1016/j.snb.2017.05.169
Biagini D, Lomonaco T, Ghimenti S, Bellagambi FG, Onor M, Scali MC, Barletta V, Marzilli M, Salvo P, Trivella MG, Fuoco R, Di Francesco F. Determination of volatile organic compounds in exhaled breath of heart failure patients by needle trap micro-extraction coupled with gas chromatography-tandem mass spectrometry. Journal of Breath Research 2017; 11, 047110. 10.1088/1752-7163/aa94e7
Salvo P, Ferrari C, Persia R, Ghimenti S, Lomonaco T, Bellagambi F, Di Francesco F. A dual mode breath sampler for the collection of the end-tidal and dead space fractions. Medical Engineering & Physics 2015; 37, 539‒544. 10.1016/j.medengphy.2015.03.013
Ghimenti S, Tabucchi S, Bellagambi FG, Lomonaco T, Onor M, Trivella MG, Fuoco R, Di Francesco F. Determination of sevoflurane and isopropyl alcohol in exhaled breath by thermal desorption gas chromatography-mass spectrometry for exposure assessment of hospital staff Journal of Pharmaceutical and Biomedical Analysis ; 106, 218‒223. 10.1016/j.jpba.2014.11.052
Ghimenti S, Lomonaco T, Bellagambi FG, Tabucchi S, Onor M, Trivella MG, Ceccarini A, Fuoco R, Di Francesco F. Comparison of sampling bags for the analysis of volatile organic compounds in breath Journal of Breath Research 2015; 9, 047110. 10.1088/1752-7155/9/4/047110
Martelli A, Testa L, Citi V, Marino A, Bellagambi FG, Ghimenti S, Breschi MC, Calderone V. Pharmacological characterization of the vascular effects of aryl isothiocyanates: Is hydrogen sulfide the real player? Vascular Pharmacology 2014; 60, 32‒41. 10.1016/j.vph.2013.11.003