Ongoing projects funded through call for proposals
NANOBRAIN – Imaging inflammation in vivo in ischemic stroke : development of a multimodal NANOprobe & BRAIN imaging methods – Further information on ANR web site
Funded by the French National Research Agency (ANR), grant agreement n°ANR-15-CE18-0026 – Duration: 42 months, 2015 – 2019
Partners: CREATIS – Centre de Recherche en Acquisition et Traitement de l’Image pour la Santé – (coordination), CSPBAT Chimie, Structures, Propriétés de Biomatériaux et d’Agents Thérapeutiques, INMG – Institut NeuroMyoGène, Institut Albert Bonniot – AICD, Laboratoire de chimie – LC ENS, MATHYM (Spin-off), Institute of Analytical Science – ISA, University of Aarhus (DK)
Objective (Extract of the summary on ANR website) NanoBrain is based on the ground-breaking concept of using Mac-1, an integrin widely used by neuropathologists and basic scientists to assess neuroinflammation, as a translational imaging target in stroke. Our specific aims are two-fold: 1) To develop a multimodal imaging probe (MRI, spectral CT, intravital microscopy) with optimal properties for in-vivo molecular imaging and a safe profile; and 2) To establish the proof-of-concept that Mac-1 imaging is valuable and feasible in rodent models of stroke.
Note: the liste above only contains non confidential and ongoing projects