Maggy HOLOGNE

Doctor
work phone: 0437423545

Research

Structural and dynamical characterization of protein / protein interaction in the liquid state by means of NMR spectroscopy. Small-angle X-Ray scattering used in a complementary fashion to get structural arrangement of protein complex. NMR and SAXS experimental data combined to molecular dynamics calculations to understand biological processes.

Biography

Maggy Hologne is currently Assistant Professor (Maître de conference) in the department of Chemistry and Biochemistry at the University of Lyon (France). She obtained her M.Sc in chemical physics in 2000 and received her Ph.D. degree in chemical physics from the University of Strasbourg in 2003 under the supervision of Jérôme Hirschinger. She studied the structure and dynamics of supramolecular complex in the solid state using NMR spectroscopy. She joined Pr. Dr. Bernd Reif’s lab in 2004 at the Forschungsinstitute für Molekülare Pharmakologie in Berlin as a postdoctoral fellow. Her project was the methodological developments of 2D and 3D solid-state NMR sequences applied to a-spectrin SH3 domain. In 2005, she moved to the Institut des Sciences Analytiques where she focused her research on protein / protein interaction by NMR, SAXS and computational methods based on GPU technology.

Publications

Publications HAL de Maggy,Hologne

2018

Journal articles

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Po-Chia Chen, Maggy Hologne, Olivier Walker, Janosch Hennig. Ab Initio Prediction of NMR Spin Relaxation Parameters from Molecular Dynamics Simulations. Journal of Chemical Theory and Computation, American Chemical Society, 2018, 14 (2), pp.1009 - 1019. ⟨10.1021/acs.jctc.7b00750⟩. ⟨hal-01767727⟩
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Amina Boughougal, Fatma Zohra Cherchali, Amel Messai, Nina Attik, Dominique Decoret, et al.. New model of metalloantibiotic: synthesis, structure and biological activity of a zinc( ii ) mononuclear complex carrying two enrofloxacin and sulfadiazine antibiotics. New Journal of Chemistry, Royal Society of Chemistry, 2018, 42 (18), pp.15346-15352. ⟨10.1039/c8nj01774c⟩. ⟨hal-01900225⟩
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Valentin Chabert, Maggy Hologne, Olivier Sénèque, Olivier Walker, Katharina Fromm. Alpha-helical folding of SilE models upon Ag(His)(Met) motif formation. Chemical Communications, Royal Society of Chemistry, 2018, 54 (74), pp.10419 - 10422. 〈10.1039/c8cc03784a〉. 〈hal-01900232〉
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2017

Journal articles

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V. Chabert, Maggy Hologne, O. Sénéque, A. Crochet, Olivier Walker, et al.. Model peptide studies of Ag + binding sites from the silver resistance protein SilE. Chemical Communications, Royal Society of Chemistry, 2017, 53 (45), pp.6105 - 6108. 〈10.1039/c7cc02630g〉. 〈hal-01546472〉
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Po-Chia Chen, Maggy Hologne, Olivier Walker. Computing the rotational diffusion of biomolecules via molecular dynamics simulation and quaternion orientations . Journal of Physical Chemistry B, American Chemical Society, 2017, 121 (8), pp.1812-1823. ⟨10.1021/acs.jpcb.6b11703⟩. ⟨hal-01520066⟩
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2016

Journal articles

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Virginie Ladroue, Anaïs Stemmelen, Fabrice Besacier, Maggy Hologne. Les NPS en vogue en région Rhône-Alpes : rapport de cas. Toxicologie Analytique et Clinique, 2016, 28 (4), pp.311-322. 〈10.1016/j.toxac.2016.03.006〉. 〈hal-01546484〉
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Maggy Hologne, Xavier Cantrelle, Gwladys Riviere, Florence Guillière, Xavier Trivelli, et al.. NMR Reveals the Interplay among the AMSH SH3 Binding Motif, STAM2, and Lys63-Linked Diubiquitin.. Journal of Molecular Biology, Elsevier, 2016, 428 (22), pp.4544-4558. ⟨10.1016/j.jmb.2016.10.002⟩. ⟨hal-01546483⟩
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Mélanie Rigard, Jeanette E. Bröms, Amandine Mosnier, Maggy Hologne, Amandine Martin, et al.. Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence. PLoS Pathogens, Public Library of Science, 2016, 12 (9), pp.article number: e1005821. ⟨10.1371/journal.ppat.1005821⟩. ⟨hal-01546486⟩
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2015

Journal articles

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Maggy Hologne, Alexandra Gaubert, Sanglar Corinne, Claire Bordes, Hervé Casabianca. New validation of molecular mass measurements by means of 2D DOSY H-1 NMR experiments: application to surfactants. Comptes Rendus Chimie, Elsevier Masson, 2015, 18 (2), pp.187-192. 〈10.1016/j.crci.2014.05.008〉. 〈hal-01187373〉
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2013

Journal articles

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Virginie Ladroue, Fabrice Besacier, Maggy Hologne. Découverte d'un laboratoire de conditionnement de nouveaux produits de synthèse en France. Annale de Toxicologie Analytique, EDP sciences, 2013, 25 (4), pp.175 -184. 〈10.1051 / ata / 2013052〉. 〈hal-00967466〉
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2012

Journal articles

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Anja Lange, Mouhamad-Baligh Ismail, Gwladys Rivière, Maggy Hologne, Denis Lacabanne, et al.. Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR. FEBS Letters, Wiley, 2012, 586 (19), pp.3379-3384. ⟨10.1016/j.febslet.2012.07.047⟩. ⟨hal-00819142⟩
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Gwladys Rivière, Maggy Hologne, Olivier Marcillat, Jean-Marc Lancelin. Dynamical properties of the loop 320s of substrate-free and substrate-bound muscle creatine kinase by NMR. FEBS Journal, Wiley, 2012, 279 (16), pp.2863-2875. ⟨10.1111/j.1742-4658.2012.08667.x⟩. ⟨hal-00873868⟩
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