Karine FAURE

CNRS researcher
work phone: 0437423686

Research

Focused on the preparative aspects of chromatography, her main objectives aim at an increasingly predictive understanding and valorization of liquid-liquid chromatography, also named centrifugal partition chromatography or countercurrent chromatography.
Concerned with the sustainability of chromatographic techniques, she tries to transfer somehow the Green Chemistry principles to preparative chromatography. This implies the search of safer and/or biorenewable solvents, the optimization of isolation processes aiming at less sample, less solvent and less energy consumption, through predictive calculation and the use of miniaturized instruments for method development purposes.
Her attention is currently turned towards how multi-dimensional chromatography could benefit to a preparative scheme.

Biography

Dr Karine Faure graduated from the Ecole Nationale Supérieure de Chimie de Tousouse (now ENSIACET) and received an Msc degree in Analytical Chemistry from University College Cork (Ireland). Her PhD research focused on the use of capillary zone electrophoresis to monitor metal complexation and was completed in the group of Prof Jeremy D Glennon in 2006. She then joined University Claude Bernard Lyon 1 as postdoctorant in the group of Jean-Louis Rocca, where she dedicated her research to the miniaturization of electrochromatography technique in thermoplastic chip via in-situ organic monolith synthesis. She was appointed tenured researcher at CNRS (chargé de recherché) in 2007. From 2010 she orientated her interest towards another chromatographic technique named centrifugal partition chromatography and received her Habilitation (HDR) in 2013, allowing full PhD supervision and own research steering. She has supervised 5 PhD students and over 15 MSc students.
Concerning institutional appointments, Dr. Karine Faure was elected member of the Unit council (2010-2016), serves as Axis coordinator for Separation Sciences at ISA since 2015 and provides tutorship to the newly created ISA board of young researchers (ISAToPE).

She is member of the editorial board of Journal of Chromatography and Related Technologies (2014-) and Journal of Pharmaceutical Analysis (2016-). She is permanent member of the International Commitee of CCC conferences (2016-) and of the executive board of Club Lyonnais de Chromatography, a network of over 110 members (2013-). She took part of the organizing committee of SEP2015 conference.

She is the author of over 30 publications in international journals and 7 invited book chapters. Her work was presented as oral and poster communications in over 70 national and international conferences amongst which 6 invited talks.

Keywords

separation; chromatography; purification and separation processes

Publications

Direction of books or issues of journals – books – book chapters

Publications HAL de karine,faure

2016

Book sections

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Karine Faure. Chromatographie de partage centrifuge. Principes et applications.. Chromatographie et techniques séparatives, Editions T.I., pp.P1496, 2016. 〈hal-01515525〉
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2015

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Alain Berthod, Karine Faure. Separations with a Liquid Stationary Phase: Countercurrent Chromatography or Centrifugal Partition Chromatography. Anderson J. L., Berthod A., Pino Estévez V., Stalcup A. M. Analytical Separation Science, 4, Wiley-VCH Verlag GmbH & Co. KGaA., pp.1177-1206, 2015, 9783527678129. 〈10.1002/9783527678129.assep046〉. 〈hal-01255453〉
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Yoann Ladner, Gérard Crétier, Karine Faure. Electrochromatography on acrylate-based monolith in cyclic olefin copolymer microchip: an attractive technology. Van Schepdael A. (Ed). Microchip capillary electrophoresis protocols., 1274, Springer Science+Business Media, pp.161-167, 2015, Methods in molecular biology, 978-1-4939-2352-6. 〈10.1007/978-1-4939-2353-3_14〉. 〈hal-01187522〉
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Alain Berthod, Karine Faure. Solvents in chromatography and electrophoresis. Anderson J. L., Berthod A., Pino Estévez V., Stalcup A. M. Analytical Separation Science, 1, Wiley-VCH Verlag GmbH & Co. KGaA., pp.135-158, 2015, 9783527678129. 〈10.1002/9783527678129.assep007〉. 〈hal-01356733〉
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2014

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Karine Faure, Nazim Mekaoui, Alain Berthod. Saving solvents in chromatographic purifications: the counter-current chromatography technique. Inamuddin, D., Mohammad, A. (Eds.). Green chromatographic techniques. Separation and purification of organic and inorganic analytes, Springer, pp.1-18, 2014, 978-94-007-7734-7. 〈hal-00983090〉
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Articles in peer-review journals since 2011


Publications HAL de Karine,Faure

2017

Journal articles

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Léa Marlot, Magali Batteau, Marie-Claire Escofet, Sylvie Nuccio, Véronique Coquoin, et al.. Two-dimensional multi-heart cutting centrifugal partition chromatography–liquid chromatography for the preparative isolation of antioxidants from Edelweiss plant. Journal of Chromatography A, Elsevier, 2017, 1504, pp.55-63. 〈10.1016/j.chroma.2017.04.056〉. 〈hal-01569418〉
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Fériel Bouiche, Karine Faure. In-situ protein determination to monitor contamination in a centrifugal partition chromatograph. Analytical Biochemistry, Elsevier Masson, 2017, 525, pp.23-28. 〈10.1016/j.ab.2017.02.015〉. 〈hal-01518929〉
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Josiane Saadé, Nina Declas, Pedro Marote, Claire Bordes, Karine Faure. Functionalization of cyclic olefin copolymer substrates with polyethylene glycol diacrylate for the in situ synthesis of immobilized nanoparticles. Journal of Materials Science, Springer Verlag, 2017, 52 (8), pp.4509-4520. 〈10.1007/s00216-016-0066-z〉. 〈hal-01515322〉
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Léa Marlot, Karine Faure. Preparative two dimensional separations involving liquid–liquid chromatography. Journal of Chromatography A, Elsevier, 2017, 1494, pp.1-17. 〈10.1016/j.chroma.2017.03.031〉. 〈hal-01515553〉
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José Cheel, Petra Urajová, Jan Hájek, Pavel Hrouzek, Marek Kuzma, et al.. Separation of cyclic lipopeptides puwainaphycins from cyanobacteria by CCC combined with polymeric resins and HPLC. Analytical and Bioanalytical Chemistry, Springer Verlag, 2017, 409 (4), pp.917-930. 〈10.1007/s00216-016-0066-z〉. 〈hal-01515308〉
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2016

Journal articles

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Norbert Fumat, Alain Berthod, Karine Faure. Effect of operating parameters on a centrifugal partition chromatography separation . Chinese Journal of Chromatography, Elsevier, 2016, 1474, pp.47-58 〈10.1016/j.chroma.2016.10.014〉. 〈hal-01515264〉
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Elodie Bouju, Alain Berthod, Karine Faure. Carnosol purification. Scaling-up centrifugal partition chromatography separations. Journal of Chromatography A, Elsevier, 2016, 1466, pp.59-66 〈10.1016/j.chroma.2016.08.015〉. 〈hal-01515260〉
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Josiane Saadé, Claire Bordes, Guy Raffin, Marie Hangouët, Pédro Marote, et al.. Response surface optimization of miniemulsion: application to UV synthesis of hexyl acrylate nanoparticles. Colloid and Polymer Science, Springer Verlag, 2016, 294 (1), pp.27-36. 〈10.1007/s00396-015-3778-2〉. 〈hal-01252718〉
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2015

Journal articles

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Elodie Bouju, Alain Berthod, Karine Faure. Scale-up in centrifugal partition chromatography: The “free-space between peaks” method. Journal of Chromatography A, Elsevier, 2015, 1409, pp.70-78. 〈10.1016/j.chroma.2015.07.020〉. 〈hal-01186354〉
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Alain Berthod, Karine Faure. Revisiting resolution in hydrodynamic countercurrent chromatography: Tubing bore effect. Journal of Chromatography A, Elsevier, 2015, 1390, pp.71-77. 〈10.1016/j.chroma.2015.02.053〉. 〈hal-01164863〉
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2014

Journal articles

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Karine Faure, Elodie Bouju, J. Doby, Alain Berthod. Limonene in Arizona liquid systems used in countercurrent chromatography. II Polarity and stationary-phase retention. Analytical and Bioanalytical Chemistry, Springer Verlag, 2014, 406 (24), pp.5919-5926. 〈10.1007/s00216-014-8030-2〉. 〈hal-01073273〉
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Karine Faure, Elodie Bouju, Pauline Suchet, Alain Berthod. Limonene in Arizona liquid systems used in countercurrent chromatography. I Physicochemical properties.. Analytical and Bioanalytical Chemistry, Springer Verlag, 2014, 406 (24), pp.5909-5917. 〈10.1007/s00216-014-8005-3〉. 〈hal-01073271〉
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2013

Journal articles

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Karine Faure, Elodie Bouju, Pauline Suchet, Alain Berthod. Use of limonene in countercurrent chromatography: a green alkane substitute.. Analytical Chemistry, American Chemical Society, 2013, 85 (9), pp.4644-4650. 〈10.1021/ac4002854〉. 〈hal-00876113〉
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Karine Faure, Nazim Mekaoui, Jérémy Meucci, Alain Berthod. Solvent selection in countercurrent chromatography using small-volume hydrostatic columns. LCGC North America, Advanstar Communications Inc, 2013, 31 (2), pp.132-143. 〈hal-00859788〉
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A. Assoumani, M. Margoum, Y. Lassalle, Bernard Herbreteau, Karine Faure, et al.. Polydimethylsiloxane Rods for the Passive Sampling of Pesticides in Surface Waters. Water, 2013, 5, p. 1366 - p. 1379. 〈10.3390/w5031366〉. 〈hal-00873142〉
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2012

Journal articles

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Yoann Ladner, Gérard Crétier, Karine Faure. Electrochromatography on acrylate-based monolith in cyclic olefin copolymer microchip: A cost-effective and easy-to-use technology. ELECTROPHORESIS, Wiley-VCH Verlag, 2012, 33 (19-20), pp.3087-3094. 〈10.1002/elps.201200238〉. 〈hal-00799854〉
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Yoann Ladner, Gérard Crétier, Karine Faure. Fabrication of acrylate monolith using photopolymerization: Effect of light intensity on electrochromatographic performance. Journal of Separation Science, Wiley-VCH Verlag, 2012, 35 (15), pp.1940-1944. 〈10.1002/jssc.201200165〉. 〈hal-00799846〉
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Nazim Mekaoui, Karine Faure, Alain Berthod. Advances in countercurrent chromatography for protein separations. Bioanalysis, 2012, 4 (7), pp.833-844. 〈10.4155/BIO.12.27〉. 〈hal-00799824〉
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Clément Faye, Joseph Chamieh, Thomas Moreau, Fabien Garnier, Karine Faure, et al.. In situ characterization of antibody grafting on porous monolithic supports. Analytical Biochemistry, Elsevier Masson, 2012, 420 (2), pp.147-154. 〈10.1016/j.ab.2011.09.016〉. 〈hal-00698239〉
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Yoann Ladner, Anthony Bruchet, Gérard Crétier, Vincent Dugas, Jérôme Randon, et al.. New "one-step" method for the simultaneous synthesis and anchoring of organic monolith inside COC microchip channels. Lab on a Chip, Royal Society of Chemistry, 2012, 12 (9), pp.1680-1685. 〈10.1039/c2lc21211k〉. 〈hal-00799836〉
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