The axis involves thirteen scientists and support staff as well as about twenty PhD students and Postdoctoral fellows, bringing together a variety of complementary competences related to the design and production of devices with specific surface properties for analytical chemistry, including in particular various types of micro/nano (bio) sensors, integrated or not into analytical microsystems.
The axis focuses on surface analysis, micro/nanostructuration of surfaces, control of surface chemistry, reactivity of bio-interfaces, electrochemistry. This multi-competence axis is composed of project-driven groups. Devices exhibiting specific surface properties are developed for many materials applications (metals, polymers,…) and micro/nano (bio)sensors (for the most part electrochemical ones) are developed for environmental, health and food applications (fast, cost effective and multiplexed analytical methods suitable for the monitoring of environmental and food contamination, toxicological impact assessment, medical diagnosis and therapeutic applications).
In the latter context, (bio)sensors appear very exciting alternatives or complementary techniques to conventional chemical methods. For (bio)functionalized microdevices, either in-situ analyses, point-of-care diagnostics and/or personalized medicine are targeted. Other devices exhibiting specific surface properties include metals and nanoparticle patterns for applications not only in sensors and lab on chips but also in plasmonics, chemistry, catalysis, and solar energy. More specifically, target applications are either cost effective compared to conventional lithography or surfaces that cannot be obtained using conventional lithography e.g. patterning on non planar substrates and applications on polymers, ceramic or carbon.
The axis is composed of three groups (see below)

Axis Managers


Interfaces & Biosensors

The main activities of the group are focused on the conception and elaboration of biofunctionnalized microdevices for biosensing , medical diagnosis and therapeutic applications. For sensing applications, we design and engineer surfaces and layers, including recognizing (bio)molecule layers, well adapted to various electrochemical transducers (amperometric, conductometric, impedancemetric, etc.). The team has acquired a strong expertise […]


Micro & Nanobiotechnology

Within the fields of nanobioscience, micro&nanotechnology, electrical engineering, and applied physics the group develops biosensors and unconventional micro&nanotechnologies to create flexible analytical tools based on BioLab-on-chips, micro/nanosensors, micromixers, and microfilters. These innovative tools, designed to be suitable for large-scale production at low cost have application in healthcare and life sciences, ranging from uncovering and diagnosing […]


Separative Methods

Based on both thermodynamic and kinetic approaches of transfer processes in separation tools, the group develops separation methodologies to tackle characterization of complex samples within the fields of environment, health, nuclear and industrial analysis. Research is driven by the reduction in size of separation devices and the development of innovative stationary phases (monolith) and coatings […]



Key research effort of the group is the control of surface physico-chemical properties using a large set of surface analysis (spectroscopy, microscopy, wettability) and surface modification (a.o. micro-nanostructuration) techniques. Original methodologies are developed including the application of various soft-lithography techniques for high resolution and high density 2D and 3D patterns. Development of surface analysis methodologies […]